If you are looking to increase your potency in the yield you can pinch or top the main cola/shoot during vegetation to render additional colas. Both techniques can be applied when the plant has 4 to 5 nodes. Pinching will yield 2 – 4 colas, topping will yield 2 colas.
Pinching: Pinch the newest formed leaves (top growth) at the top of the main cola (you don’t have to break them off but it is ok if they are removed)
Topping: The main cola is removed (cut) right above the second leaves (node) from the top
** These techniques render different results and can be used throughout the growth cycle but the plant has to recover before it is applied a second, third, fourth time … etc.